drug trials

Revealed: drug firms funding UK patient groups that lobby for NHS approval of medicines

“Observer investigation shows that majority of Nice drug appraisals involve groups financially linked to maker of pharmaceuticals“ Shanti Das and Jon Ungoed-Thomas report for The Observer: “Drug companies are systematically funding grassroots patient groups that lobby the  NHS  medicines watchdog to approve…
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Dr. Jason Fung: Financial Conflicts of Interests and the End of Evidence-Based Medicine

The producers of this 50 minute video say: “‘Evidence-based medicine is actually so corrupt as to be useless or harmful,’ Marcia Angell wrote in 2009. The statement was less a revelation than something many already knew, but it made waves because…
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What did the scientific literature learn from internal company documents in the pharmaceutical industry? A scoping review

This review by Marc-André Gagnon and Miaoran Dong has been published in Cochrane Evidence Synthesis and Methods. The abstract says: “Objective To identify all scientific papers that used internal industry documents in the pharmaceutical sector and analyze what and how the…
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Most people on antidepressants don’t need them: time to wean them off

This leader-article comes from The Economist. It begins: “Almost 35 years ago American drug regulators approved Prozac, the first in a series of blockbuster antidepressants known as selective serotonin re-uptake inhibitors (SSRIs). Prozac and its cousins were lauded by patients and…
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The Emperor’s New Drugs : Antidepressants and the Placebo Effect

This free course (from Mad in America Continuing Education) includes a lecture video from Prof. Irving Kirsch (Associate Director of the Program in Placebo Studies and lecturer in medicine at the Harvard Medical School and Beth Israel Deaconess Medical Center), together with…
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Interview: Researchers Deconstruct Ghostwritten Industry Trial for Antidepressant

“… articles go through a lot of drafts, maybe 10-15 drafts, that get passed around between the statisticians and the marketing people at the companies and then, after most of this has already been written, they go looking for the…
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Secrets of the drug trials

Panorama is a BBC TV programme that specialises in investigative journalism. In 2007 they broadcast “Secrets of the drug trials” (see video below), concerning which the BBC said: “Secret emails reveal that the UK’s biggest drug company distorted trial results…
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Drug trials ‘skewed by the pharmaceutical industry,’ GPs say

A report by Laura Donnelly in The Telegraph (June 2017) notes that: “Four in five GPs believe drug trials are skewed by the pharmaceutical industry, amid widespread mistrust in medical research, polling shows. A report by the Academy of Medical Sciences is…
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