Randomised Control Trials (RCTs)

Which depression measure is best?

“In the systematic review of 450 clinical trials on unipolar & bipolar depression, we identify 388 outcomes & compares their performance. Which measure performs best?” Eiko Fried reports : “A new  paper published today  in Lancet Psychiatry, led by Christopher Veal, reports findings from a…
Read more

It’s Health’s Illusions I Recall, I Really Don’t Know Health at All

This article from David Healy and Harriet Vogt has been published by Mad in America. It begins: “There is a core concept shaping the ‘market’ in health, the concept of an assay, that few doctors or patients understand. Even fewer spot…
Read more

The Wild Doctor – Le Médecin Sauvage

This blog post has been published by RxISK (who describe themselves as ‘… a free, independent drug safety website to help you weigh the benefits of any medication against its potential dangers”). It begins: “The French playwright Moliere loved poking fun at…
Read more

RELEASE (REdressing Long-tErm Antidepressant uSE): protocol for a 3-arm pragmatic cluster randomised controlled trial effectiveness-implementation hybrid type-1 in general practice

The abstract for this research protocol (published by BMC) says: “Background Many people experience withdrawal symptoms when they attempt to stop antidepressants. Withdrawal symptoms are readily misconstrued for relapse or ongoing need for medication, contributing to long-term use (> 12 months). Long-term antidepressant use…
Read more

Changing the topic does not change the facts

This letter to The Lancet Psychiatry (journal) comes from Dr. Jonanathan Shedler. It begins: “In a Comment published in The Lancet Psychiatry, Scott Lilienfeld and colleagues 1 wrote that I encouraged psychotherapists to ignore new practice guidelines for post-traumatic stress disorder (PTSD) because…
Read more

Misreporting Results and Publication Bias Common in Psychiatry Research

This report by Zenobia Morrill has been published by Mad in America. It begins: “A new paper in Schizophrenia Bulletin presents evidence that publication bias and outcome reporting bias in psychiatry research are common and concerning. These biases overestimate the efficacy of psychiatric…
Read more

My Mind Medicine Australia Psychedelic Lecture Tour

This article by Prof. David Nutt has been published by Drug Science. It begins: “I have just come back from a 3-week lecture tour of South-Eastern Australia supporting the cause of the charity  Mind Medicine Australia  (MMA)  They have been raising money for psychedelic…
Read more

Single-dose psilocybin-assisted therapy in major depressive disorder: A placebo-controlled, double-blind, randomised clinical trial

This research paper has been published in eClinicalMedicine. The summary says: “Background Psilocybin has been suggested as a novel, rapid-acting treatment for depression. Two consecutive doses have been shown to markedly decrease symptom severity in an open-label setting or when compared to…
Read more

ECT is a classic failure of evidence-based medicine

This Council for Evidence-Based Psychiatry has hosted a guest-blog by Prof. Richard Bentall, who writes: “In a discipline to which controversy is no stranger, there are few controversies guaranteed to generate as much heat as that surrounding the benefits and costs…
Read more

Follow

Get the latest posts delivered to your mailbox:

Your email address will not be passed to any other organisation. It will only be used to send you new posts made on this website.

MENU