Research

The Serotonin Zombie: Authors of New Study Try to Breathe New Life into the Dead

Peter Simons reports for Mad in the UK: “In June, Joanna Moncrieff and others had appeared to put the final dagger into the low serotonin theory of depression (the so-called ;chemical imbalance’ theory). They reviewed fifty years of research into the…
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Depression Not So “Treatment-Resistant” After Psychodynamic Psychotherapy

“Researcher finds Intensive Short-Term Psychodynamic Psychotherapy reduced depressive symptoms in patients who did not improve with pharmacological treatment.“ This report by Dr. José Giovanni Luiggi-Hernández has been published by Mad in America. It begins: “A recent study published in Psychotherapy suggests that Intensive…
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Study highlights growing diversity of mental health models

This report by Justin Karter has been published by Mad in the UK. It begins: “Mental health, a topic traditionally dominated by psychiatric and psychological theories, is undergoing a profound evolution. A recent study highlights the increased richness and diversity of…
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Seven lifestyle changes that lower risk of depression

Sarah Knapton reports for The Telegraph: “Moderate drinking and a good night’s sleep are among seven healthy lifestyle changes that can more than halve the risk of depression, scientists have found. Experts at the University of Cambridge examined health data from…
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Beyond the Chemical Imbalance Theory of Depression: An Interview with Prof. Joanna Moncrieff

This interview , conducted by Justin Garson, has been published in Psychology Today. It begins: “KEY POINTS In 2022, a large review led by Joanna Moncrieff showed the ‘serotonin theory of depression’ to be groundless. Her review puts into question our…
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RELEASE (REdressing Long-tErm Antidepressant uSE): protocol for a 3-arm pragmatic cluster randomised controlled trial effectiveness-implementation hybrid type-1 in general practice

The abstract for this research protocol (published by BMC) says: “Background Many people experience withdrawal symptoms when they attempt to stop antidepressants. Withdrawal symptoms are readily misconstrued for relapse or ongoing need for medication, contributing to long-term use (> 12 months). Long-term antidepressant use…
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Psychobiotics and the need for better interventional data

This article (with relevance to mental health) has been published in BMC Medicine. It begins: “Gut microbiota composition has been associated with multiple health outcomes: various studies employing predictive genetic studies and randomised controlled trials suggest this is the case. More…
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Prenatal Antidepressant Exposure and Offspring Brain Morphologic Trajectory

This research paper has been published in JAMA Psychiatry. Key Points: Question: Is intrauterine exposure to selective serotonin reuptake inhibitors (SSRIs) and prenatal or postnatal depressive symptoms associated with brain morphologic trajectory in offspring? Findings: In this cohort study of 3198 mother-infant…
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