Research

The Effectiveness of an Intensive Inpatient Psychotherapy Program for Chronic Depression: A naturalistic comparison with wait list

This paper has been published by BMC Psychiatry. The abstract says: “Background Patients with chronic depression (CD) typically have an early symptom onset, more psychiatric comorbidities, more treatment attempts, and more frequent and longer inpatient hospitalizations than patients with major depressive…
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Withdrawal Syndrome Following Discontinuation of 28 Antidepressants: Pharmacovigilance Analysis of 31,688 Reports from the WHO Spontaneous Reporting Database

“Antidepressants are associated with an increased reporting of withdrawal syndrome compared with other drug classes.” This open-access research article by multiple co-authors has been provided by Springer Link. The abstract says: “Introduction Evidence is lacking on withdrawal syndrome related to individual antidepressants…
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“Clear evidence” for serotonin hypothesis of depression?

This post by Dr. Eiko Fried has been published on his blog site Measurement, modeling & complexity of mental health. It begins: “There has been a 60 year long discussion on the role of the neurotransmitter serotonin in the pathophysiology of…
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Despite More Treatments for Depression, Prevalence Doesn’t Decrease—Why?

This article by Peter Simons has been published on the Mad in the UK website. It begins: “Between 1987 and 2007, the number of people receiving treatment for depression in the United States increased fourfold (and has continued to rise more…
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Magic-mushroom drug can treat severe depression, trial suggests

This report by Philippa Roxby comes from the BBC. It begins: “A drug based on a compound in hallucinogenic mushrooms can improve the symptoms of severe depression for up to 12 weeks, a trial shows. A 25mg tablet of psilocybin puts…
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Methodological Flaws, Conflicts of Interest, and Scientific Fallacies: Implications for the Evaluation of Antidepressants’ Efficacy and Harm

This paper by Michael Hengartner has been published in the journal Frontiers in Psychiatry. The abstract says: “Background In current psychiatric practice, antidepressants are widely and with ever-increasing frequency prescribed to patients. However, several scientific biases obfuscate estimates of antidepressants’ efficacy…
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The illusion of evidence based medicine

“Evidence based medicine has been corrupted by corporate interests, failed regulation, and commercialisation of academia, argue these authors” This article by Jon Jureidini and Leemon B. McHenry has been published in the British Medical Journal. It begins (with footnotes excluded, but…
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Critical Suicidology: Transforming Suicide Research and Prevention for the 21st Century

This book has been co-authored by Jennifer White, Ian Marsh, Michael J. Kral, and Jonathan Morris. The publishers say: “In Critical Suicidology, a team of international scholars, practitioners, and people directly affected by suicide argue that the field of suicidology has…
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