Research

Psychedelic frees up depressed brain, study shows

Philippa Roxby reports for the BBC: “Psilocybin, a drug found in magic mushrooms, appears to free up the brains of people with severe depression in a way that other antidepressants do not, a study has found. The results, based on brain…
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Overuse of Psychiatric Drugs is Worsening Public Mental Health, Doctor Argues

This article by Richard Sears has been published by Mad in America. It begins: “In a new article published in the Journal of Addictive Disorders and Mental Health, Jose Luis Turabian, a professor of medicine at Complutense University in Spain, explores the biological…
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Prescribing Antipsychotics in First Episode Psychosis

This course by Dr. Lex Wunderink (professor at the University of Gronigen in the Netherlands) is provided for free (or else a voluntary donation) by Mad in America Continuing Education. Subtitled “Is Less More?”, the course includes: IntroductionLecture videoDownload of lecture…
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Common Statistical Method Conflates Withdrawal with Relapse

“Researchers argue that common study methods for psychiatric drugs may inadvertently minimize withdrawal effects and inflate drug efficacy.“ This article by Peter Simons has been published by Mad in America. It begins: “Survival analysis is a statistical technique often used to…
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Association between patient beliefs regarding assigned treatment and clinical response: reanalysis of data from the Hypericum Depression Trial Study Group

This study has been published on the PubMed website. The abstract says: “Objective: To reanalyze data from a 2002 study by the Hypericum Depression Trial Study Group to determine whether patients who believed they were receiving active therapy rather than placebo obtained…
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Extraordinary Science and Psychiatry: Responses to the Crisis in Mental Health Research

This book has been written by Jeffrey Poland and Serife Tekin. The abstract says: “The subject of the book is the culture of crisis and controversy that exists in contemporary mental health research, following the publication of the fifth edition of…
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Antidepressants might be largely ineffective, study suggests

The Daily Telegraph reports : “Antidepressants should be prescribed less routinely by doctors, scientists have said, after a study concluded there was no strong evidence that the drugs were effective. New research has indicated the side effects many patients suffer from…
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Evidence-biased Antidepressant Prescription: Overmedicalisation, Flawed Research, and Conflicts of Interest

This book has been written by Michael P. Hengartner. The publishers say: “This book addresses the over-prescribing of antidepressants in people with mostly mild and subthreshold depression. It outlines the steep increase in antidepressant prescription and critically examines the current scientific…
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Intensive Home Treatment for Acute Mental Disorders: An Alternative to Hospitalization

This article by David Heath has been published by Mad in America. It begins: “In 1978, I became the medical director of a general hospital psychiatric unit serving the twin cities of Kitchener/Waterloo in southwestern Ontario, Canada. Over the next four…
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New Study Finds Depression in Older Adults Could Be Prevented With Sleep Training

This study – “Prevention of Incident and Recurrent Major Depression in Older Adults With Insomnia: A Randomized Clinical Trial” – has been published in the journal JAMA Psychiatry. It found that older adults who underwent cognitive therapy for insomnia were 50%…
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