depression

Which depression measure is best?

“In the systematic review of 450 clinical trials on unipolar & bipolar depression, we identify 388 outcomes & compares their performance. Which measure performs best?” Eiko Fried reports : “A new  paper published today  in Lancet Psychiatry, led by Christopher Veal, reports findings from a…
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Placebo Effect – not antidepressants – responsible for depression improvement

This report by Peter Simons has been published by Mad in the UK. It begins: “In a study of fluoxetine (Prozac) for adolescents, researchers found that the placebo effect predicted good outcomes, but the actual drug treatment did not. After accounting…
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Suicide Rates and Prescription of Antidepressants

This study by Simone Amendola, Martin Plöderl, and Michael P. Hengartner has been published by Crisis (The Journal of Crisis Intervention and Suicide Prevention). The abstract says: “Background: Previous ecological studies reported that increasing antidepressant prescriptions were associated with decreasing suicide rates. …
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Watchful waiting for depression using depathologization, advice and shared decision making

Highlights: Watchful waiting was shown to be an effective first line of treatment for non-suicidal patients with depressive symptoms Patients already arrive with expectations so depathologization should be addressed Expectation of pharmacotherapy before the arrival was the main driver of…
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Bad Feelings, Best Explanations: In Defence of the Propitiousness Theory of the Low Mood System

This paper by James Turner has been published by Erkenntnis. The abstract says: “There are three main accounts of the proper function of the low mood system (LMS): the social risk theory, the disease theory, and the propitiousness theory. Adjudicating between…
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Seven reasons why most Major Depression is probably not a brain disorder

This article by Ed Hagen has been published on the Grasshoppermouse website. It begins: “Virtually all mental health researchers accept that Major Depression (MD) is a mental disorder, i.e., a brain dysfunction. I argue that this widespread belief should instead be…
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