Research

Which depression measure is best?

“In the systematic review of 450 clinical trials on unipolar & bipolar depression, we identify 388 outcomes & compares their performance. Which measure performs best?” Eiko Fried reports : “A new  paper published today  in Lancet Psychiatry, led by Christopher Veal, reports findings from a…
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Abuse is main driver of mental ill health in women and girls, say psychiatrists

This article by Denis Campbell has been published in The Guardian. It begins: “Abuse and violence  suffered by women and girls  is the main reason they are much more likely than men and boys to develop mental ill health, Britain’s psychiatrists say. Experiencing such behaviour can…
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Open-door policy versus treatment-as-usual in urban psychiatric inpatient wards: a pragmatic, randomised controlled, non-inferiority trial in Norway

The abstract of this trial has been published in The Lancet Psychiatry: “Background Open-door policy is a recommended framework to reduce coercion in psychiatric wards. However, existing observational data might not fully capture potential increases in harm and use of coercion…
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Placebo Effect – not antidepressants – responsible for depression improvement

This report by Peter Simons has been published by Mad in the UK. It begins: “In a study of fluoxetine (Prozac) for adolescents, researchers found that the placebo effect predicted good outcomes, but the actual drug treatment did not. After accounting…
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ADHD may have been an evolutionary advantage, research suggests

This report by Nicola Davis has been published in The Guardian. It begins: “Traits common to attention deficit hyperactivity disorder (ADHD), such as distractibility or impulsivity, might have been an evolutionary advantage for our ancestors by improving their tactics when foraging…
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Why do patients want medication free treatment for psychosis? An explorative study on reasons for applying to medication free programs

This research paper from Elisabeth C. Klæbo Reitan, Valentina C. Iversen, Henriette Riley, and Anne Høye has been published in BMC Psychiatry. The abstract says: “Background A focus on patient’s and service user’s perspectives regarding long-term antipsychotic treatment led to a declaration…
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Suicide Rates and Prescription of Antidepressants

This study by Simone Amendola, Martin Plöderl, and Michael P. Hengartner has been published by Crisis (The Journal of Crisis Intervention and Suicide Prevention). The abstract says: “Background: Previous ecological studies reported that increasing antidepressant prescriptions were associated with decreasing suicide rates. …
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Watchful waiting for depression using depathologization, advice and shared decision making

Highlights: Watchful waiting was shown to be an effective first line of treatment for non-suicidal patients with depressive symptoms Patients already arrive with expectations so depathologization should be addressed Expectation of pharmacotherapy before the arrival was the main driver of…
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Probiotics for adults with major depressive disorder compared with antidepressants: a systematic review and network meta-analysis

This review has been published in the journal Oxford Academic. The abstract says: “Context: Despite recent advances in antidepressants in treating major depression (MDD), their usage is marred by adverse effects and social stigmas. Probiotics may be an efficacious adjunct or…
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