Mark Horowitz

Antidepressants Work Better Than Sugar Pills Only 15 Percent of the Time

This article by Adam Piore has been published in Newsweek magazine. It begins: “Five years ago Mark Horowitz seemed an unlikely skeptic of psycho-pharmaceuticals. He had been taking the popular antidepressant Lexapro virtually every day for 15 years. He was so…
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Personal Perspective on the Systematic Review of Serotonin Imbalance Hypothesis for depression and Mechanism of Action for Antidepressants

This interview with Dr. Mark Horowitz is conducted by Fauzia Khan and has been published in The Physician. The abstract says: “Fauzia Khan meets Dr Mark Horowitz, Trainee Psychiatrist and Clinical Research Fellow in the NHS. Mark talks about his journey…
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A Decisive Blow to the Serotonin Hypothesis of Depression

This article by Christopher Lane has been published in Psychology Today. It begins: “Almost as soon as it was floated in 1965 by Harvard psychiatrist Joseph Schildkraut, the serotonin hypothesis of  depression —reduced and simplified by pharma marketing to the ‘chemical imbalance’…
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Is the chemical imbalance an ‘urban legend’? An exploration of the status of the serotonin theory of depression in the scientific literature

This study/article by Benjamin Anga, MarkHorowitz and Joanna Moncrieff has been published in ScienceDirect. The abstract says: “The theory that depression is caused by a serotonin abnormality or other chemical imbalance has become widely accepted by the public and is one…
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Listening to the Patient Voice: The Antidepressant Withdrawal Experience

“’A total of 97% of respondents were offered a prescription on their initial consultation with a doctor, 5% reported being offered talking therapy, and 0.6% were offered lifestyle advice (with some patients offered more than one option).’According to the researchers,…
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There’s More To Life Than Happiness

“I think it’s not just that you pursue a project beyond yourself because it will make you happy, but that you pursue a project beyond yourself because it makes suffering worthwhile. It’s not that you do these things because the…
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New paper on how to stop antipsychotic drugs deemed ‘historic breakthrough’

“Stopping medications is an important part of the job of a psychiatrist, yet it has received relatively little attention. In clinical practice, I often see patients perking up when they reduce their antipsychotic medication, and they tell me that they…
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