Mark Horowitz
The Maudsley Guidelines for De-prescribing

The Maudsley Deprescribing Guidelines (published by Wiley) will be out in a couple of months. Co-authored by David M. Taylor and Mark Horowitz, it will contain evidenced-based taper regimens for all antidepressants and practical advice on how to do it….
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Response to Criticism of Our Serotonin Paper
Services for People Withdrawing From Antidepressants

“New study documents what antidepressant users need to help them come off safely.” Key Points: One in four people will experience severe withdrawal symptoms when trying to reduce or come off antidepressants. There are no specialized services to support people…
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After skool: Mark Horowitz – common misconceptions about depression & antidepressants

Dr. Mark Horowitz is a training psychiatrist and Clinical Research Fellow in Psychiatry at North East London NHS Foundation Trust. He has a doctorate in the neurobiology of depression and the action of antidepressants from the Institute of Psychiatry, Psychology and Neuroscience at King’s…
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Estimating Risk of Antidepressant Withdrawal from a Review of Published Data
Antidepressants Work Better Than Sugar Pills Only 15 Percent of the Time
Personal Perspective on the Systematic Review of Serotonin Imbalance Hypothesis for depression and Mechanism of Action for Antidepressants
A Decisive Blow to the Serotonin Hypothesis of Depression

This article by Christopher Lane has been published in Psychology Today. It begins: “Almost as soon as it was floated in 1965 by Harvard psychiatrist Joseph Schildkraut, the serotonin hypothesis of depression —reduced and simplified by pharma marketing to the ‘chemical imbalance’…
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Is the chemical imbalance an ‘urban legend’? An exploration of the status of the serotonin theory of depression in the scientific literature

This study/article by Benjamin Anga, MarkHorowitz and Joanna Moncrieff has been published in ScienceDirect. The abstract says: “The theory that depression is caused by a serotonin abnormality or other chemical imbalance has become widely accepted by the public and is one…
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