Mark Horowitz

Acceptability and optimisation of resources to support antidepressant cessation: A qualitative think-aloud study with patients

This study by Suzanne McDonald, Katharine Ann Wallis, Mark Horowitz, Esther Mann, Vilany Le and Maria Donald has been published in the British Journal of General Practice. The abstract says: “Background: Stopping long-term (>12 months) antidepressants can be difficult for patients…
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Response to Criticism of Our Serotonin Paper

This article by Joanna Moncrieff and Mark Horowitz has been published by Mad in America. It begins: “We recently published a  paper  finding that the serotonin hypothesis of depression (the idea that depression is caused by low serotonin or reduced serotonin activity)…
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Services for People Withdrawing From Antidepressants

“New study documents what antidepressant users need to help them come off safely.” Key Points: One in four people will experience severe withdrawal symptoms when trying to reduce or come off antidepressants. There are no specialized services to support people…
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After skool: Mark Horowitz – common misconceptions about depression & antidepressants

Dr. Mark Horowitz is a training psychiatrist and Clinical Research Fellow in Psychiatry at North East London NHS Foundation Trust. He has a doctorate in the neurobiology of depression and the action of antidepressants from the Institute of Psychiatry, Psychology and Neuroscience at King’s…
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Estimating Risk of Antidepressant Withdrawal from a Review of Published Data

This article – from Mark Abie Horowitz, Adele Framer, Michael P. Hengartner, Anders Sørensen & David Taylor – has been published in the journal CNS Drugs. The abstract says: “Adaptation of the brain to the presence of a drug predicts withdrawal…
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Antidepressants Work Better Than Sugar Pills Only 15 Percent of the Time

This article by Adam Piore has been published in Newsweek magazine. It begins: “Five years ago Mark Horowitz seemed an unlikely skeptic of psycho-pharmaceuticals. He had been taking the popular antidepressant Lexapro virtually every day for 15 years. He was so…
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Personal Perspective on the Systematic Review of Serotonin Imbalance Hypothesis for depression and Mechanism of Action for Antidepressants

This interview with Dr. Mark Horowitz is conducted by Fauzia Khan and has been published in The Physician. The abstract says: “Fauzia Khan meets Dr Mark Horowitz, Trainee Psychiatrist and Clinical Research Fellow in the NHS. Mark talks about his journey…
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A Decisive Blow to the Serotonin Hypothesis of Depression

This article by Christopher Lane has been published in Psychology Today. It begins: “Almost as soon as it was floated in 1965 by Harvard psychiatrist Joseph Schildkraut, the serotonin hypothesis of  depression —reduced and simplified by pharma marketing to the ‘chemical imbalance’…
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Is the chemical imbalance an ‘urban legend’? An exploration of the status of the serotonin theory of depression in the scientific literature

This study/article by Benjamin Anga, MarkHorowitz and Joanna Moncrieff has been published in ScienceDirect. The abstract says: “The theory that depression is caused by a serotonin abnormality or other chemical imbalance has become widely accepted by the public and is one…
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