Research

Associations between constructs related to social relationships and mental health conditions and symptoms: an umbrella review

This review has been published in BMC Psychiatry. The abstract says: “Background: Loneliness and social isolation are increasingly recognised as prevalent among people with mental health problems, and as potential targets for interventions to improve quality of life and outcomes, as…
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Acceptability and optimisation of resources to support antidepressant cessation: A qualitative think-aloud study with patients

This study by Suzanne McDonald, Katharine Ann Wallis, Mark Horowitz, Esther Mann, Vilany Le and Maria Donald has been published in the British Journal of General Practice. The abstract says: “Background: Stopping long-term (>12 months) antidepressants can be difficult for patients…
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Risk of Suicidal Behaviors and Antidepressant Exposure Among Children and Adolescents: A Meta-Analysis of Observational Studies

This meta-analysis has been published in the journal Frontiers in Psychiatry. The summary is as follows: “Objectives: Although several studies have reviewed the suicidal risk of antidepressants, the conclusions remain inconsistent. We, therefore, performed a meta-analysis of observational studies to address the…
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No benefit of antidepressants in inpatient treatment of depression. A longitudinal, quasi-experimental field study

This article by Reinhard Maß, Kerstin Backhaus, Katharina Lohrer, Michael Szelies and Bodo K. Unkelbach has been published in Psychopharmacology. The abstract says: “Rationale Antidepressants (AD) are mostly considered indispensable for the treatment of major depression. The vast majority of…
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A Neuroscientist Evaluates the Standard Biological Model of Depression

This  research article  by Peter Sterling (Professor of Neuroscience) has been published by Mad in America. It begins: “Abstract Neuroscientists widely hypothesize that ‘depression’ arises from a brain disorder caused by some defect in a specific neural pathway. If so, we might identify…
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Causality in Mental Disturbance: A Review of the Neuroscience

“To be clear: there is no neuroscience to suggest that any mental function would be improved by ablating or stimulating a particular structure in the prefrontal cortex or its associated subcortical regions. To the contrary, what we know of the intrinsic organization…
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Framing Depression as a Functional Signal Rather than a Disease Promotes Hope and Reduces Stigma, Study Finds

This report from Julia Lejeune has been published by Mad in America. It begins: “New research reveals that individuals seeking depression treatment may benefit from an explanation of depression as serving an important human function, as opposed to a disease arising…
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Rates of Prolonged Grief Disorder: Considering relationship to the person who died and cause of death

This research paper – from Kara Thieleman, Joanne Cacciatore, and Allen Frances – has been published in the Journal of Affective Disorders. The abstract says: Background Prolonged Grief Disorder (PGD) was recently included in DSM-5-TR. The rate of PGD is known to…
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How did mental health become so biomedical? The progressive erosion of social determinants in historical psychiatric admission registers

This paper – available via Research Gate in the ‘History of Psychiatry’ category – is co-authored by Fritz Handerer, Peter Kinderman, Carsten Timmermann, and Sara J Tai. The abstract says: “This paper explores the historical developments of admission registers of psychiatric…
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Are antidepressants effective in the treatment of depression in the elderly? A critical umbrella review on reviews, methods, and future perspectives

This umbrella review from Dr. Michael F. Hvidberg has been published in the journal Mental Health Science. The abstract says: “The elderly are currently the most frequent users of antidepressants across ages, despite having a high risk of adverse effects (AEs). This literature…
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