chemical imbalance theory

Antidepressants Work Better Than Sugar Pills Only 15 Percent of the Time

This article by Adam Piore has been published in Newsweek magazine. It begins: “Five years ago Mark Horowitz seemed an unlikely skeptic of psycho-pharmaceuticals. He had been taking the popular antidepressant Lexapro virtually every day for 15 years. He was so…
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Personal Perspective on the Systematic Review of Serotonin Imbalance Hypothesis for depression and Mechanism of Action for Antidepressants

This interview with Dr. Mark Horowitz is conducted by Fauzia Khan and has been published in The Physician. The abstract says: “Fauzia Khan meets Dr Mark Horowitz, Trainee Psychiatrist and Clinical Research Fellow in the NHS. Mark talks about his journey…
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Remembering a Quarter of a Million “Mental Patients” Murdered in the 1930s and 1940s

This article by Dr. John Read has been published in Psychology Today. It begins: “In 1941, the staff of the Hadamar  Psychiatric  Institution—psychiatrists, nurses and secretaries—attended a ceremony and were each given a bottle of beer. The occasion was the murder of…
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How to take the news that depression has not been shown to be caused by a chemical imbalance

This article is from psychiatrist Dr. Joanna Moncrieff. It begins: “For decades people have been told that depression is caused by a serotonin deficiency. This was the rationale behind the introduction of the SSRI (Selective Serotonin Reuptake Inhibitor) antidepressants in the…
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A Decisive Blow to the Serotonin Hypothesis of Depression

This article by Christopher Lane has been published in Psychology Today. It begins: “Almost as soon as it was floated in 1965 by Harvard psychiatrist Joseph Schildkraut, the serotonin hypothesis of  depression —reduced and simplified by pharma marketing to the ‘chemical imbalance’…
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Is the chemical imbalance an ‘urban legend’? An exploration of the status of the serotonin theory of depression in the scientific literature

This study/article by Benjamin Anga, MarkHorowitz and Joanna Moncrieff has been published in ScienceDirect. The abstract says: “The theory that depression is caused by a serotonin abnormality or other chemical imbalance has become widely accepted by the public and is one…
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Effects of a chemical imbalance causal explanation on individuals’ perceptions of their depressive symptoms

This study by Joshua Kemp, James Lickel and Brett Deacon has been published in Behaviour Research and Therapy. The abstract says: “Although the chemical imbalance theory is the dominant causal explanation of depression in the United States, little is known about…
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