serotonin

“Clear evidence” for serotonin hypothesis of depression?

This post by Dr. Eiko Fried has been published on his blog site Measurement, modeling & complexity of mental health. It begins: “There has been a 60 year long discussion on the role of the neurotransmitter serotonin in the pathophysiology of…
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How to take the news that depression has not been shown to be caused by a chemical imbalance

This article is from psychiatrist Dr. Joanna Moncrieff. It begins: “For decades people have been told that depression is caused by a serotonin deficiency. This was the rationale behind the introduction of the SSRI (Selective Serotonin Reuptake Inhibitor) antidepressants in the…
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A Decisive Blow to the Serotonin Hypothesis of Depression

This article by Christopher Lane has been published in Psychology Today. It begins: “Almost as soon as it was floated in 1965 by Harvard psychiatrist Joseph Schildkraut, the serotonin hypothesis of  depression —reduced and simplified by pharma marketing to the ‘chemical imbalance’…
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Is the chemical imbalance an ‘urban legend’? An exploration of the status of the serotonin theory of depression in the scientific literature

This study/article by Benjamin Anga, MarkHorowitz and Joanna Moncrieff has been published in ScienceDirect. The abstract says: “The theory that depression is caused by a serotonin abnormality or other chemical imbalance has become widely accepted by the public and is one…
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Primum non nocere: an evolutionary analysis of whether antidepressants do more harm than good

This review has been published on the PubMed website. The abstract says: “Antidepressant medications are the first-line treatment for people meeting current diagnostic criteria for major depressive disorder. Most antidepressants are designed to perturb the mechanisms that regulate the neurotransmitter serotonin…
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Time for Some Serious Thought about ‘Antidepressants’

This blog post (2016) from Peter Hitchens has been published in the Daily Mail. It begins: “I expect to have more to say about this, but today’s BMJ? UCL/ Nordic Cochrane Centre analysis of research on ‘antidepressants’ should surely change the terms…
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A Mind of Your Own: The Truth about Depression and How Women Can Heal Their Bodies to Reclaim Their Lives

This book has been written by Dr. Kelly Brogan. The publishers say: “Depression is one of the UK’s leading causes of disability. One in four women in their 40s are prescribed antidepressant drugs BUT depression is a sign of malfunction of…
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Gut feelings: The microbes involved in our mental health

Writing for the Glasgow Insight into Science & Technology (GIST), Carolina Guidolin reports : “Normally, around 1014 (one hundred trillion) microorganisms live in our gut, supporting our health in many ways, from providing essential vitamins to helping our immune systems develop 1 ….
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