antidepressants

NHS Data: 41% Rise in Antidepressant Prescribing to Children Aged 5-12 Since 2015

This report comes from Mad in America. It begins: “From The Pharmaceutical Journal: ‘NHS data obtained via a freedom of information request, provided on 10 August 2021, show a steady increase over the past six years in the number of unique…
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Psychedelic frees up depressed brain, study shows

Philippa Roxby reports for the BBC: “Psilocybin, a drug found in magic mushrooms, appears to free up the brains of people with severe depression in a way that other antidepressants do not, a study has found. The results, based on brain…
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Is the chemical imbalance an ‘urban legend’? An exploration of the status of the serotonin theory of depression in the scientific literature

This study/article by Benjamin Anga, MarkHorowitz and Joanna Moncrieff has been published in ScienceDirect. The abstract says: “The theory that depression is caused by a serotonin abnormality or other chemical imbalance has become widely accepted by the public and is one…
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Primum non nocere: an evolutionary analysis of whether antidepressants do more harm than good

This review has been published on the PubMed website. The abstract says: “Antidepressant medications are the first-line treatment for people meeting current diagnostic criteria for major depressive disorder. Most antidepressants are designed to perturb the mechanisms that regulate the neurotransmitter serotonin…
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Association between patient beliefs regarding assigned treatment and clinical response: reanalysis of data from the Hypericum Depression Trial Study Group

This study has been published on the PubMed website. The abstract says: “Objective: To reanalyze data from a 2002 study by the Hypericum Depression Trial Study Group to determine whether patients who believed they were receiving active therapy rather than placebo obtained…
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Antidepressants might be largely ineffective, study suggests

The Daily Telegraph reports : “Antidepressants should be prescribed less routinely by doctors, scientists have said, after a study concluded there was no strong evidence that the drugs were effective. New research has indicated the side effects many patients suffer from…
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Evidence-biased Antidepressant Prescription: Overmedicalisation, Flawed Research, and Conflicts of Interest

This book has been written by Michael P. Hengartner. The publishers say: “This book addresses the over-prescribing of antidepressants in people with mostly mild and subthreshold depression. It outlines the steep increase in antidepressant prescription and critically examines the current scientific…
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Antidepressants do not work better than a placebo, study finds

Eleanor Hayward Health, reporting for the Daily Mail, writes : “Doctors should stop prescribing antidepressants because there is no decent clinical evidence that they work better than a placebo, a study has found. About one in six British adults take the…
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Time for Some Serious Thought about ‘Antidepressants’

This blog post (2016) from Peter Hitchens has been published in the Daily Mail. It begins: “I expect to have more to say about this, but today’s BMJ? UCL/ Nordic Cochrane Centre analysis of research on ‘antidepressants’ should surely change the terms…
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The Illusion of Evidence-Based Medicine: Exposing the crisis of credibility in clinical research

This book has been co-authored by Prof. Jon Jureidini and Dr. Leemon McHenry. The publishers say: “An exposé of the corruption of medicine by the pharmaceutical industry at every level, from exploiting the vulnerable destitute for drug testing, through manipulation of…
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