a coherent system

“Clear evidence” for serotonin hypothesis of depression?

This post by Dr. Eiko Fried has been published on his blog site Measurement, modeling & complexity of mental health. It begins: “There has been a 60 year long discussion on the role of the neurotransmitter serotonin in the pathophysiology of…
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Despite More Treatments for Depression, Prevalence Doesn’t Decrease—Why?

This article by Peter Simons has been published on the Mad in the UK website. It begins: “Between 1987 and 2007, the number of people receiving treatment for depression in the United States increased fourfold (and has continued to rise more…
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Methodological Flaws, Conflicts of Interest, and Scientific Fallacies: Implications for the Evaluation of Antidepressants’ Efficacy and Harm

This paper by Michael Hengartner has been published in the journal Frontiers in Psychiatry. The abstract says: “Background In current psychiatric practice, antidepressants are widely and with ever-increasing frequency prescribed to patients. However, several scientific biases obfuscate estimates of antidepressants’ efficacy…
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Indicative Trauma Impact Manual 2023

This manual is currently on pre-order, with a release date of 1st March 2023. The publishers say: “A non-diagnostic, trauma-informed guide to emotion, thought, and behaviour. This must-have manual presents the first trauma-informed, non-diagnostic alternative to other manuals of mental health…
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Celexa, Lexapro & the Death of Evidence-Based Medicine

This article has been published on the website of American legal firm Baum Hedlund Aristei & Goldman. It begins: “‘Oh, what a tangled web we weave. When first we practise to deceive!” From Walter Scott’s epic poem, Marmion. This is the story of…
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More treatment but no less depression: The treatment-prevalence paradox

This article – by Johan Orme, Steven D. Hollon, Ronald C. Kessler, Pim Cuijpers, and Scott M. Monroe – has been published in the Clinical Psychology Review. The abstract says: “Treatments for depression have improved, and their availability has markedly increased…
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Studying Mental Health Problems as Systems, Not Syndromes

This article by Eiko I. Fried has been published in Sage Journals. The abstract says: “Despite decades of clinical, sociopolitical, and research efforts, progress in understanding and treating mental health problems remains disappointing. I discuss two barriers that have contributed to…
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The illusion of evidence based medicine

“Evidence based medicine has been corrupted by corporate interests, failed regulation, and commercialisation of academia, argue these authors” This article by Jon Jureidini and Leemon B. McHenry has been published in the British Medical Journal. It begins (with footnotes excluded, but…
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Do adult mental health services identify child abuse and neglect? A systematic review

This review – by John Read, David Harper, Ian Tucker, and Angela Kennedy – has been published on the PubMed website. The abstract says: “Child abuse and neglect play a causal role in many mental health problems. Knowing whether users of…
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